Episode 3 of our monthly GU Cast Journal Club and today we focus on one classic paper in Urology, and one from recent times - the ERSPC randomised trial of screening in prostate cancer, and the NIAGARA trial evaluating peri-operative immunotherapy in muscle-invasive bladder cancer. We are delighted to welcome back our GU Cast Journal Club Editors, Dr Carlos Delgado (Melbourne, AUS), and Dr Elena Berg (Munich, GER), along with main GU Cast Hosts, Renu Eapen and Declan Murphy. Watch out for Declan getting all misty-eyed recalling when the ERSPC was published back in 2009 (the rest of the team are too young to remember this)!

A Masterclass in advanced kidney cancer today with the great Danny Heng (University of Calgary, Canada), and our own Lewis Au (Peter MacCallum Cancer Centre, Melbourne)! Both popped into the GU Cast studio while Danny was in Australia doing some lectures and visiting us at Peter Mac. We challenged Danny and Lewis to simplify three hot topics in kidney cancer, ideal if (like us) you find it difficult to keep up with this fast-moving area. The three areas are: 1. What sort of patient is this? Risk stratification made easy (by Danny, Master of the universe of Risk Stratification in kidney cancer) 2. Novel scans and biomarkers in kidney cancer - a bluffers guide 3. Neoadjuvant and adjuvant therapies in kidney cancer - what the urologist needs to know

A cracking overview of management options for advanced renal cancer, with Regina Barragan-Carillo and Tian Zhang. This is a Themed Podcast supported by our Bronze Partners, Ipsen Pharmaceuticals